Investigating how certain genetic variations affect blood pressure regulation
Genes regulated by BP Noncoding SNPs in Relevant Cells
['FUNDING_P01'] · UNIVERSITY OF ARIZONA · NIH-10903753
This study is looking at how certain genetic differences can affect blood pressure by influencing how genes work, and it's designed to help people understand their own genetics better, which could lead to more personalized treatments for managing blood pressure.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ARIZONA (nih funded) |
| Locations | 1 site (TUCSON, UNITED STATES) |
| Trial ID | NIH-10903753 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how specific genetic variations, known as noncoding SNPs, influence blood pressure by regulating gene expression. The study employs advanced methodologies to explore the functional effects of these SNPs, particularly those located far from protein-coding genes. By examining how these genetic factors interact with different cell types, the research aims to uncover the complex mechanisms behind blood pressure regulation. Patients may benefit from insights that could lead to personalized treatments based on their genetic profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of high blood pressure or those diagnosed with hypertension.
Not a fit: Patients with blood pressure issues that are solely due to lifestyle factors without any genetic predisposition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing and treating high blood pressure based on individual genetic makeup.
How similar studies have performed: Previous studies have shown promising results in understanding genetic influences on blood pressure, suggesting that this approach could yield valuable insights.
Where this research is happening
TUCSON, UNITED STATES
- UNIVERSITY OF ARIZONA — TUCSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIANG, MINGYU — UNIVERSITY OF ARIZONA
- Study coordinator: LIANG, MINGYU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.