Investigating how certain fatty acids affect colorectal cancer risk
Polyunsaturated fatty acids and colorectal tumor risk: a molecular and genetic epidemiology study
['FUNDING_OTHER'] · VANDERBILT UNIVERSITY MEDICAL CENTER · NIH-10772000
This study is looking at how certain healthy fats, like omega-3 and omega-6, might affect the risk of getting colorectal tumors, and it’s for anyone interested in understanding how these fats and our genes could play a role in preventing cancer.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY MEDICAL CENTER (nih funded) |
| Locations | 1 site (NASHVILLE, UNITED STATES) |
| Trial ID | NIH-10772000 on ClinicalTrials.gov |
What this research studies
This research explores the relationship between polyunsaturated fatty acids (PUFAs) and the risk of developing colorectal tumors. It focuses on the effects of omega-6 and omega-3 fatty acids, particularly how they influence inflammation and cancer development. By utilizing advanced genetic analysis techniques, the study aims to identify genetic variants that may affect how these fatty acids are metabolized in the body. Participants' blood and tissue samples will be analyzed to better understand these associations and their implications for cancer prevention.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of colorectal cancer or those at high risk for developing this condition.
Not a fit: Patients who have already been diagnosed with advanced colorectal cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary recommendations or interventions that reduce the risk of colorectal cancer.
How similar studies have performed: Previous research has shown promising results in understanding the role of fatty acids in cancer risk, suggesting that this approach could yield valuable insights.
Where this research is happening
NASHVILLE, UNITED STATES
- VANDERBILT UNIVERSITY MEDICAL CENTER — NASHVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KHANKARI, NIKHIL KISHOR — VANDERBILT UNIVERSITY MEDICAL CENTER
- Study coordinator: KHANKARI, NIKHIL KISHOR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.