Investigating how certain drugs may affect Alzheimer's disease outcomes.
Official title: Analysis of Alzheimer's disease studies that feature truncated or interval-censored covariates
Funded at University of Massachusetts Amherst · NIH-10901990 · Data updated 2026-11-12
This study is looking at how certain medications might help people with Alzheimer's by improving the way we analyze past research, so we can get better answers about their effects.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Massachusetts Amherst NIH-funded |
| Lab location | 1 site (Hadley, United States) |
| Project start | August 15, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $238,405 |
| NIH project number | 5R21AG083468-02 |
| Project ID | NIH-10901990 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for Alzheimer's disease or those already diagnosed with Alzheimer's or related dementias.
✕Less likely to help
Patients with non-Alzheimer's related forms of dementia or those not at risk for Alzheimer's may not benefit from this research.
What this research studies
This research focuses on understanding the effects of drug exposure on Alzheimer's disease by analyzing existing studies that have not fully accounted for certain data limitations. The researchers aim to develop new methods to address issues like incomplete data and measurement errors, which can lead to biased results. By applying these methods to specific case studies, they hope to provide clearer insights into how repurposed drugs might help reduce the risk of Alzheimer's or slow its progression. This work is crucial as it seeks to improve the understanding of treatment effects in a complex disease like Alzheimer's.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment strategies for Alzheimer's disease, potentially improving patient outcomes.
How similar studies have gone: Previous research has shown promise in repurposing drugs for Alzheimer's treatment, but this approach of addressing data limitations is relatively novel.
Where this research is happening
-
University of Massachusetts Amherst
Hadley, United States Active
Researchers
- Principal investigator: Qian, Jing — University of Massachusetts Amherst
- Study coordinator: Qian, Jing
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.