Investigating how certain disinfectants may harm lung function
Mitochondrial-mediated Lung Injury mechanisms of QACs in vivo
This study is looking at how certain disinfectants might affect lung health, especially how they could harm lung cells, and it aims to help people understand the safety of the products they use every day.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-10675747 on NIH RePORTER |
What this research studies
This research examines the effects of quaternary ammonium salts (QACs), commonly found in disinfectants, on lung health. It focuses on how these chemicals can lead to mitochondrial dysfunction in lung cells, potentially causing respiratory issues. By analyzing human exposure data and conducting in vivo experiments, the study aims to understand the mechanisms behind lung injury linked to QACs. Patients may benefit from insights into the safety of disinfectants they encounter daily.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who frequently use disinfectants containing QACs and may experience respiratory symptoms.
Not a fit: Patients who do not use QAC-containing products or have no respiratory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved safety regulations for disinfectants, protecting lung health for millions of Americans.
How similar studies have performed: Previous studies have indicated potential health risks associated with QAC exposure, suggesting that this research builds on established findings rather than exploring entirely novel territory.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Cortopassi, Gino a — University of California at Davis
- Study coordinator: Cortopassi, Gino a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.