Investigating how certain chemicals may lead to type 2 diabetes in diverse populations.
Perfluoroalkyl substances and incident type 2 diabetes in a multi-ethnic population: A metabolome-genome investigation
This study is looking at how certain chemicals found in everyday products might affect your chances of getting type 2 diabetes, by checking blood samples from people before they develop the condition, and it's designed for anyone interested in understanding the health risks linked to these chemicals.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10862866 on NIH RePORTER |
What this research studies
This research explores the link between exposure to perfluoroalkyl substances (PFAS), a group of chemicals found in many everyday products, and the risk of developing type 2 diabetes (T2D). By analyzing blood samples from individuals before they are diagnosed with T2D, the study aims to understand how these chemicals interact with genetic factors to influence diabetes risk. The research employs advanced techniques to examine both the genetic and metabolic changes associated with PFAS exposure, focusing on a multi-ethnic population to address existing health disparities.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse ethnic backgrounds, particularly those at risk for type 2 diabetes due to genetic or environmental factors.
Not a fit: Patients who do not have any risk factors for type 2 diabetes or are not exposed to PFAS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for type 2 diabetes, particularly in at-risk populations.
How similar studies have performed: While there is growing evidence linking PFAS exposure to health issues, this specific integrated approach to studying its effects on diabetes is relatively novel and has not been extensively tested.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Valvi, Damaskini — Icahn School of Medicine at Mount Sinai
- Study coordinator: Valvi, Damaskini
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.