Investigating how certain cells contribute to the spread of lung cancer.
Official title: Macrophages and fibroblasts in the progression of lung cancer
Funded at Stanford University · NIH-11232009 · Data updated 2026-11-12
This study is looking at how certain immune and connective tissue cells in the lungs might affect the growth of lung cancer in women who have had breast cancer, with the hope of finding new ways to treat the disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 1, 2023 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $88,618 |
| NIH project number | 4K00CA284357-03 |
| Project ID | NIH-11232009 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with postpartum breast cancer within 10 years of childbirth.
✕Less likely to help
Patients with lung cancer unrelated to postpartum conditions may not receive direct benefits from this research.
What this research studies
This research focuses on understanding the role of macrophages and fibroblasts in the progression of lung cancer, particularly in postpartum breast cancer patients. By examining how these cells interact within the tumor microenvironment, the study aims to uncover mechanisms that may lead to increased metastasis. The approach includes both rodent models and human patient data to provide a comprehensive view of cancer progression. Patients may benefit from insights that could lead to new therapeutic strategies targeting these specific cells.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and better survival rates for patients with lung cancer.
How similar studies have gone: Previous research has shown promising results in understanding the tumor microenvironment and its role in cancer metastasis, indicating that this approach has potential for success.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Ozaki, Michelle Kayoko — Stanford University
- Study coordinator: Ozaki, Michelle Kayoko
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.