Investigating how certain cell receptors contribute to pain in oral cancer
Endosomal mechanisms signaling oral cancer pain
This study is looking into how certain cell receptors might be causing pain for people with oral cancer, and by gathering information from patients about their pain and tumor samples, researchers hope to better understand how this pain happens and find ways to help.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10786660 on NIH RePORTER |
What this research studies
This research explores the role of specific receptors in cells that may be responsible for pain experienced by patients with oral cancer. It focuses on how these receptors, located in endosomes, send signals that can lead to chronic pain. By collecting data from oral cancer patients, including their pain experiences and tumor samples, the study aims to understand the mechanisms behind pain signaling. The research employs a reverse translational approach, which means it uses findings from patients to inform laboratory studies and vice versa.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with oral cancer who are experiencing pain.
Not a fit: Patients without a diagnosis of oral cancer or those not experiencing pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that alleviate pain for patients suffering from oral cancer.
How similar studies have performed: Other research has shown promise in understanding pain mechanisms through similar receptor signaling approaches, indicating potential for success in this area.
Where this research is happening
New York, United States
- New York University — New York, United States (Active)
Researchers
- Principal investigator: Schmidt, Brian L — New York University
- Study coordinator: Schmidt, Brian L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.