Investigating how certain brain mechanisms affect learning and behavior.
Project 2
This study is looking at how the brain keeps itself balanced and healthy, especially in people with neurodevelopmental disorders, by exploring how certain signals affect brain connections and behavior, which could help us understand learning and adaptability better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10907598 on NIH RePORTER |
What this research studies
This research explores the molecular mechanisms behind homeostatic synaptic plasticity, which acts as a corrective measure to balance brain activity. By studying both animal models and human neurons, the project aims to understand how disruptions in this process may lead to cognitive deficits, particularly in neurodevelopmental disorders. The researchers will analyze the effects of retinoic acid signaling on synaptic function and behavior in enriched environments, providing insights into how these mechanisms influence learning and flexibility in behavior.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with neurodevelopmental disorders, particularly those experiencing cognitive deficits.
Not a fit: Patients without neurodevelopmental disorders or those who do not exhibit cognitive deficits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for improving cognitive function in individuals with neurodevelopmental disorders.
How similar studies have performed: Previous research has shown promising results in understanding synaptic plasticity and its implications for cognitive function, suggesting that this approach has the potential for significant findings.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Chen, Lu — Emory University
- Study coordinator: Chen, Lu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.