Investigating how certain brain cells affect memory loss in Alzheimer's disease
Official title: The role of oligodendrocyte precursor cells in circuit remodeling in the mature brain
Funded at Johns Hopkins University · NIH-10931376 · Data updated 2026-11-12
This study is looking at special brain cells called oligodendrocyte precursor cells to see how they might affect memory loss in people with Alzheimer's disease, hoping to find new ways to help improve brain health as we age.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $53,974 |
| NIH project number | 5F30AG084193-02 |
| Project ID | NIH-10931376 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 and older who are experiencing symptoms of Alzheimer's disease.
✕Less likely to help
Patients under the age of 65 or those without Alzheimer's disease may not receive any benefit from this research.
What this research studies
This research focuses on understanding the role of oligodendrocyte precursor cells (OPCs) in the brain, particularly how they may influence memory loss associated with Alzheimer's disease (AD). By examining these cells, the research aims to uncover their potential contributions to the progression of AD and how they interact with neurons in the aging brain. The study will utilize advanced techniques to analyze the behavior and characteristics of OPCs in both healthy and AD-affected brains, providing insights into their function and potential therapeutic targets.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating or managing Alzheimer's disease by targeting the mechanisms involving oligodendrocyte precursor cells.
How similar studies have gone: Previous research has shown promising results in understanding the roles of glial cells in neurodegenerative diseases, indicating that this approach may yield valuable insights.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Kim, Anya — Johns Hopkins University
- Study coordinator: Kim, Anya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.