Investigating how cerebrospinal fluid affects brain health in children with congenital heart disease
Quantitative Magnetic Resonance Properties of Cerebrospinal Fluid and Brain Health Outcomes in Pediatric Congenital Heart Disease
This study is looking at how the fluid around the brain and spine might affect the thinking and development of children with congenital heart disease, hoping to find ways to help them do better in life.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10894327 on NIH RePORTER |
What this research studies
This research focuses on understanding the relationship between cerebrospinal fluid (CSF) properties and neurodevelopmental outcomes in children with congenital heart disease (CHD). It aims to identify how variations in CSF volume and flow dynamics may contribute to cognitive deficits and other neurodevelopmental challenges faced by these children. By analyzing CSF characteristics, the study seeks to uncover potential risk factors that could lead to improved interventions and support for affected children. The research employs advanced imaging techniques to quantitatively assess CSF properties and their impact on brain health.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with congenital heart disease, particularly those experiencing neurodevelopmental challenges.
Not a fit: Patients without congenital heart disease or those who do not exhibit neurodevelopmental deficits may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cognitive impairments in children with congenital heart disease.
How similar studies have performed: Previous studies have shown that alterations in cerebrospinal fluid are linked to neurological conditions, suggesting that this research could build on established findings.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Lee, Vincent Kyu — University of Pittsburgh at Pittsburgh
- Study coordinator: Lee, Vincent Kyu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.