Investigating how cerebellar synaptic dysfunction relates to autism spectrum disorder

Cerebellar Synaptic Dysfunction in Autism Spectrum Disorder

['FUNDING_R03'] · COLORADO STATE UNIVERSITY · NIH-11036053

This study is looking at how changes in a part of the brain called the cerebellum might affect people with autism, helping us understand the condition better and possibly leading to new ways to support those with autism as they grow up.

Quick facts

Phase['FUNDING_R03']
Study typeNih_funding
SexAll
SponsorCOLORADO STATE UNIVERSITY (nih funded)
Locations1 site (FORT COLLINS, UNITED STATES)
Trial IDNIH-11036053 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the role of the cerebellum in autism spectrum disorder (ASD) by examining how synaptic and biophysical development in neural circuits is disrupted. Researchers will use experimental models to explore the effects of these disruptions on brain function, particularly in adulthood. The study aims to identify specific changes in cerebellar circuits that may contribute to the symptoms of ASD, which could lead to new insights into treatment options.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with autism spectrum disorder, particularly those who are adults or transitioning into adulthood.

Not a fit: Patients without a diagnosis of autism spectrum disorder or those with other unrelated neurological conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of ASD and lead to improved therapeutic strategies for individuals affected by the disorder.

How similar studies have performed: Previous research has shown promising results in understanding the role of cerebellar dysfunction in ASD, suggesting that this approach could yield valuable insights.

Where this research is happening

FORT COLLINS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder, autistic spectrum disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.