Investigating how cerebellar synaptic dysfunction relates to autism spectrum disorder
Official title: Cerebellar Synaptic Dysfunction in Autism Spectrum Disorder
Funded at Colorado State University · NIH-11036053 · Data updated 2026-11-12
This study is looking at how changes in a part of the brain called the cerebellum might affect people with autism, helping us understand the condition better and possibly leading to new ways to support those with autism as they grow up.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project start | February 1, 2025 |
| Project end | January 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $73,274 |
| NIH project number | 1R03MH138898-01 |
| Project ID | NIH-11036053 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with autism spectrum disorder, particularly those who are adults or transitioning into adulthood.
✕Less likely to help
Patients without a diagnosis of autism spectrum disorder or those with other unrelated neurological conditions may not benefit from this research.
What this research studies
This research focuses on understanding the role of the cerebellum in autism spectrum disorder (ASD) by examining how synaptic and biophysical development in neural circuits is disrupted. Researchers will use experimental models to explore the effects of these disruptions on brain function, particularly in adulthood. The study aims to identify specific changes in cerebellar circuits that may contribute to the symptoms of ASD, which could lead to new insights into treatment options.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of ASD and lead to improved therapeutic strategies for individuals affected by the disorder.
How similar studies have gone: Previous research has shown promising results in understanding the role of cerebellar dysfunction in ASD, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Colorado State University
Fort Collins, United States Active
Researchers
- Principal investigator: Vaaga, Christopher Edward — Colorado State University
- Study coordinator: Vaaga, Christopher Edward
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.