Investigating how centrosome instability contributes to prostate cancer
Centrosome instability as a mechanism to promote localized prostate cancer
This study is looking at how problems with tiny structures in our cells, called centrosomes, might contribute to prostate cancer, with the hope of finding better ways to diagnose and treat the disease for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10664978 on NIH RePORTER |
What this research studies
This research explores the role of centrosome instability in the development of prostate cancer. It focuses on understanding how the loss or abnormal amplification of centrosomes in prostate epithelial cells leads to genomic instability, which is a hallmark of cancer. By studying these cellular mechanisms, the research aims to uncover the underlying causes of prostate cancer and improve diagnostic and treatment strategies. Patients may benefit from insights that could lead to more effective therapies and better management of the disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with prostate cancer, particularly those exhibiting genomic instability.
Not a fit: Patients with prostate cancer that does not exhibit genomic instability or those with other types of cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and targeted treatments for prostate cancer.
How similar studies have performed: While the specific focus on centrosome loss in prostate cancer is novel, similar research on genomic instability in other cancers has shown promising results.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Rogers, Gregory Charles — University of Arizona
- Study coordinator: Rogers, Gregory Charles
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.