Investigating how cells move and behave in living organisms using advanced imaging techniques
High spatiotemporal optical imaging to study dynamics of 3D cell motion and behavior in living organisms
This study is all about watching how individual cells move and change shape in real-time, using special imaging techniques that are gentle on tissues, to help us learn more about how organs and tissues develop in living organisms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Arlington NIH-funded |
| Lab location | 1 site (Arlington, United States) |
| Project ID | NIH-10929383 on NIH RePORTER |
What this research studies
This research focuses on understanding the behavior and movement of individual cells in living organisms by developing advanced optical imaging techniques. It aims to track cell migration and monitor changes in cell shape and size in real-time, which are crucial for understanding processes like organ development and tissue formation. The study utilizes innovative light-sheet fluorescence microscopy to achieve high-resolution imaging while minimizing tissue damage, allowing for detailed observation of cellular interactions in three dimensions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve abnormal cell behavior or migration, such as cancer or developmental disorders.
Not a fit: Patients with stable conditions that do not involve significant cellular movement or dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding cellular behavior, which may improve treatments for various diseases related to cell dysfunction.
How similar studies have performed: Other research has shown success with advanced imaging techniques in studying cellular dynamics, indicating a promising approach for this investigation.
Where this research is happening
Arlington, United States
- University of Texas Arlington — Arlington, United States (Active)
Researchers
- Principal investigator: Lee, Juhyun — University of Texas Arlington
- Study coordinator: Lee, Juhyun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.