Investigating how cells move and behave in living organisms using advanced imaging techniques
Official title: High spatiotemporal optical imaging to study dynamics of 3D cell motion and behavior in living organisms
Funded at University of Texas Arlington · NIH-10929383 · Data updated 2026-11-12
This study is all about watching how individual cells move and change shape in real-time, using special imaging techniques that are gentle on tissues, to help us learn more about how organs and tissues develop in living organisms.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Arlington NIH-funded |
| Lab location | 1 site (Arlington, United States) |
| Project start | September 15, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $390,000 |
| NIH project number | 5R35GM150947-02 |
| Project ID | NIH-10929383 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve abnormal cell behavior or migration, such as cancer or developmental disorders.
✕Less likely to help
Patients with stable conditions that do not involve significant cellular movement or dysfunction may not benefit from this research.
What this research studies
This research focuses on understanding the behavior and movement of individual cells in living organisms by developing advanced optical imaging techniques. It aims to track cell migration and monitor changes in cell shape and size in real-time, which are crucial for understanding processes like organ development and tissue formation. The study utilizes innovative light-sheet fluorescence microscopy to achieve high-resolution imaging while minimizing tissue damage, allowing for detailed observation of cellular interactions in three dimensions.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding cellular behavior, which may improve treatments for various diseases related to cell dysfunction.
How similar studies have gone: Other research has shown success with advanced imaging techniques in studying cellular dynamics, indicating a promising approach for this investigation.
Where this research is happening
-
University of Texas Arlington
Arlington, United States Active
Researchers
- Principal investigator: Lee, Juhyun — University of Texas Arlington
- Study coordinator: Lee, Juhyun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.