Investigating how cells maintain their structure during development
Understanding developmental control of cell polarity using single-cell in vivo biochemistry
['FUNDING_R01'] · UNIVERSITY OF TEXAS AT AUSTIN · NIH-10895595
This study is looking at how cells know which way to grow and organize themselves, using tiny worms called C. elegans to see how proteins react to signals during early development, which helps us understand how healthy tissues and organs are formed.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS AT AUSTIN (nih funded) |
| Locations | 1 site (AUSTIN, UNITED STATES) |
| Trial ID | NIH-10895595 on ClinicalTrials.gov |
What this research studies
This research explores the mechanisms that control cell polarity, which is essential for proper cell function and development. By using advanced techniques to measure protein interactions in single cells, the researchers aim to understand how specific proteins respond to developmental signals in the early embryos of the model organism C. elegans. This approach allows for a detailed examination of how cells communicate and organize themselves, which is crucial for maintaining healthy tissue and organ function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cell polarity dysfunction, such as certain cancers or developmental disorders.
Not a fit: Patients with conditions unrelated to cell polarity or those who are not affected by developmental signaling pathways may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into developmental disorders and cancer by improving our understanding of cell behavior and organization.
How similar studies have performed: Previous research has shown promising results in understanding cell polarity and its implications in various diseases, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
AUSTIN, UNITED STATES
- UNIVERSITY OF TEXAS AT AUSTIN — AUSTIN, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DICKINSON, DANIEL J — UNIVERSITY OF TEXAS AT AUSTIN
- Study coordinator: DICKINSON, DANIEL J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.