Investigating how cell structures function in tiny roundworms.
Cytoskeletal Function in C. elegans Embryos
This study is looking at how tiny structures inside early worm embryos help with cell division and development, which could give us important clues about cancer and fertility that might also apply to humans.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oregon NIH-funded |
| Lab location | 1 site (Eugene, United States) |
| Project ID | NIH-11144945 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of cytoskeletal structures in the early embryos of the nematode Caenorhabditis elegans, a model organism. Using advanced techniques like live cell imaging and CRISPR/Cas9 gene editing, researchers will explore how these structures contribute to cell division and development. The study aims to uncover the mechanisms behind acentrosomal spindle assembly and the regulation of the cell cortex, which are crucial for processes related to cancer and fertility. By leveraging innovative imaging methods and genetic tools, the research seeks to provide insights that could be applicable to human health.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals affected by cancer or fertility issues.
Not a fit: Patients with unrelated health conditions or those not impacted by cancer or fertility issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new understanding and potential treatments for conditions related to cancer and fertility.
How similar studies have performed: Other research has shown success in using C. elegans as a model for studying cellular processes, indicating that this approach is well-established.
Where this research is happening
Eugene, United States
- University of Oregon — Eugene, United States (Active)
Researchers
- Principal investigator: Bowerman, Bruce a — University of Oregon
- Study coordinator: Bowerman, Bruce a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.