Investigating how cell grafts can promote healing in stroke-affected brains
Official title: Intravital Imaging of Transplant Evoked Glia Repair in Stroke
Funded at Boston University (Charles River Campus) · NIH-10869970 · Data updated 2026-11-12
This study is looking at how special cell grafts can help the brain heal after a stroke, and it's for anyone interested in new ways to improve recovery and brain health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $206,250 |
| NIH project number | 5R21NS128821-02 |
| Project ID | NIH-10869970 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have experienced an ischemic stroke.
✕Less likely to help
Patients who have not had a stroke or those with chronic neurological conditions unrelated to stroke may not benefit from this research.
What this research studies
This research focuses on understanding how cell grafts can enhance the healing process in the brain after a stroke. By using advanced imaging techniques, the study aims to observe how these grafts influence the repair of brain tissue and the behavior of glial cells, which are crucial for supporting nerve function. The researchers will track changes over time to identify the best conditions for promoting effective healing and regeneration in the adult brain. This could lead to new treatment strategies that extend beyond the immediate aftermath of a stroke.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that improve recovery and healing in stroke patients.
How similar studies have gone: While the approach of using cell grafts for brain repair is being explored, this specific application in adult stroke recovery is relatively novel and has not been extensively tested.
Where this research is happening
-
Boston University (Charles River Campus)
Boston, United States Active
Researchers
- Principal investigator: O'shea, Timothy Mark — Boston University (Charles River Campus)
- Study coordinator: O'shea, Timothy Mark
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.