Investigating how CD37 affects platelet responses in cardiovascular disease
Official title: CD37 as a Regulator of Platelet Patho(Physiological) Responses
Funded at New York University School of Medicine · NIH-10884199 · Data updated 2026-11-12
This study is looking at a protein called CD37 to see how it affects platelets in the blood, which could help us find new ways to prevent heart attacks and strokes without causing bleeding problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 15, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $579,849 |
| NIH project number | 5R01HL167917-02 |
| Project ID | NIH-10884199 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk of cardiovascular diseases, particularly those who have not yet experienced a heart attack or stroke.
✕Less likely to help
Patients who have already experienced multiple cardiovascular events or have existing severe bleeding disorders may not benefit from this research.
What this research studies
This research focuses on understanding the role of CD37, a novel regulator of platelet activation, in cardiovascular diseases such as myocardial infarction and stroke. By exploring how CD37 influences platelet behavior, the study aims to identify new therapeutic targets that could prevent these conditions without increasing the risk of bleeding. The approach includes advanced platelet sequencing to uncover the mechanisms by which platelets contribute to inflammation and atherosclerosis. This could lead to innovative treatments that improve cardiovascular health.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that prevent heart attacks and strokes by targeting platelet functions without the risk of major bleeding.
How similar studies have gone: Previous research has shown promise in targeting platelet functions for cardiovascular disease prevention, indicating that this approach could be a significant advancement in treatment options.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Barrett, Tessa — New York University School of Medicine
- Study coordinator: Barrett, Tessa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.