Investigating how cannabis use affects sleep and stress hormones

Longitudinal reciprocal relationships between cannabis use, sleep, and the HPA-axis

['FUNDING_R01'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-11221850

This study is looking at how using cannabis affects sleep and stress in young adults aged 21-29, and it will help us understand how these factors interact, especially for those who might struggle with cannabis use.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorOREGON HEALTH & SCIENCE UNIVERSITY (nih funded)
Locations1 site (PORTLAND, UNITED STATES)
Trial IDNIH-11221850 on ClinicalTrials.gov

What this research studies

This research explores the complex relationship between cannabis use, sleep patterns, and the body's stress response system in young adults. Participants aged 21-29 will engage in a three-week study where their sleep behaviors and cannabis use will be monitored through daily surveys. The study aims to understand how changes in sleep can influence cannabis consumption and vice versa, particularly focusing on individuals with varying levels of cannabis use disorder. By examining these interactions, the research seeks to uncover potential mechanisms that could inform treatment strategies for those affected by cannabis use disorder.

Who could benefit from this research

Good fit: Ideal candidates for this research are young adults aged 21-29 who either use cannabis moderately or have severe cannabis use disorder.

Not a fit: Patients outside the age range of 21-29 or those who do not use cannabis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment approaches for individuals struggling with cannabis use disorder and related sleep issues.

How similar studies have performed: Previous research has indicated a bidirectional relationship between substance use and sleep disturbances, suggesting that this approach may yield valuable insights.

Where this research is happening

PORTLAND, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: addictive disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.