Investigating how cannabis use affects sleep and stress hormones
Official title: Longitudinal reciprocal relationships between cannabis use, sleep, and the HPA-axis
Funded at Oregon Health & Science University · NIH-11221850 · Data updated 2026-11-12
This study is looking at how using cannabis affects sleep and stress in young adults aged 21-29, and it will help us understand how these factors interact, especially for those who might struggle with cannabis use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | June 15, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $395,995 |
| NIH project number | 1R01DA061251-01A1 |
| Project ID | NIH-11221850 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are young adults aged 21-29 who either use cannabis moderately or have severe cannabis use disorder.
✕Less likely to help
Patients outside the age range of 21-29 or those who do not use cannabis may not benefit from this research.
What this research studies
This research explores the complex relationship between cannabis use, sleep patterns, and the body's stress response system in young adults. Participants aged 21-29 will engage in a three-week study where their sleep behaviors and cannabis use will be monitored through daily surveys. The study aims to understand how changes in sleep can influence cannabis consumption and vice versa, particularly focusing on individuals with varying levels of cannabis use disorder. By examining these interactions, the research seeks to uncover potential mechanisms that could inform treatment strategies for those affected by cannabis use disorder.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment approaches for individuals struggling with cannabis use disorder and related sleep issues.
How similar studies have gone: Previous research has indicated a bidirectional relationship between substance use and sleep disturbances, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Bowles, Nicole P — Oregon Health & Science University
- Study coordinator: Bowles, Nicole P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.