Investigating how cannabis affects depression and brain function in young adults

Cannabis, Depression and Neurobiological Function in Transition-Age Youth

NIH-funded research Stanford University · NIH-10370928

This study is looking at how using cannabis might affect brain function and mood in young adults aged 18 to 25, and it’s inviting both regular users and non-users to participate in tests and share hair samples to see how cannabis exposure relates to mental health over a year.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10370928 on NIH RePORTER

What this research studies

This research focuses on understanding the impact of cannabis exposure on brain function and the development of depressive symptoms in transition-age youth, specifically those aged 18 to 25. The study will involve recruiting both regular cannabis users and non-users to assess their neurobiological responses through various tests, including neuroimaging and cortisol measurements. Participants will also provide hair samples to measure THC exposure over time. By following these individuals for a year, the research aims to uncover important insights into how cannabis may influence mental health during a critical developmental period.

Who could benefit from this research

Good fit: Ideal candidates for this research are transition-age youth who are regular cannabis users or non-users aged 18 to 25.

Not a fit: Patients outside the age range of 18 to 25 or those who do not use cannabis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for depression in young adults who use cannabis.

How similar studies have performed: Previous research has shown promising results in understanding the effects of cannabis on mental health, but this specific approach is relatively novel.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.