Investigating how cannabis affects cognitive impairment in people with HIV
Role of cannabis on HIV-related cognitive impairment: a brain connectomics study
This study is looking at how using cannabis might affect thinking and memory in people living with HIV, and it will help us understand how HIV changes the brain over time by tracking brain connections and cognitive skills in 200 adults.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-10890226 on NIH RePORTER |
What this research studies
This research explores the impact of cannabis use on cognitive impairment in individuals living with HIV. It aims to understand how HIV alters brain structure and function, particularly in relation to neural networks, and how cannabis may influence these changes. The study will involve analyzing brain connectivity and cognitive performance over time in a group of 200 adults with HIV, using advanced machine learning techniques to create personalized models for diagnosing and assessing the severity of cognitive impairment. Participants will undergo various assessments to track changes in brain organization and cognitive abilities.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are living with HIV and may also use cannabis.
Not a fit: Patients who do not have HIV or are under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cognitive impairment in HIV-positive individuals, potentially improving their quality of life.
How similar studies have performed: While there is ongoing research into the effects of cannabis on various neurological conditions, this specific approach combining connectomics and HIV-related cognitive impairment is relatively novel.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Meade, Christina S — Wake Forest University Health Sciences
- Study coordinator: Meade, Christina S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.