Investigating how cannabinoids affect gut health and inflammation in people with HIV
Effects of Cannabidiol and Tetrahydrocannabinol on the Microbiome, Endocannabinoids and Neuroinflammation in HIV
This study is looking at how certain compounds from cannabis, like THC and CBD, might help improve gut health and reduce inflammation in people living with HIV by examining changes in gut bacteria and immune responses.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11052555 on NIH RePORTER |
What this research studies
This research explores the relationship between the gut microbiome, endocannabinoid system, and neuroinflammation in individuals living with HIV. It aims to understand how cannabinoids like THC and CBD influence gut health and inflammation by conducting a clinical trial with participants receiving these compounds. The study will analyze changes in gut bacteria and immune responses through advanced sequencing techniques and blood tests. By comparing responses in people with and without HIV, the research seeks to uncover potential therapeutic benefits of cannabinoids.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with HIV who are interested in exploring the effects of cannabinoids on their health.
Not a fit: Patients who do not have HIV or those who are not interested in cannabinoid treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve gut health and reduce inflammation in people living with HIV.
How similar studies have performed: Previous research has shown promising results in using cannabinoids for various health conditions, but this specific approach focusing on HIV is relatively novel.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Ellis, Ronald J. — University of California, San Diego
- Study coordinator: Ellis, Ronald J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.