Investigating how cannabinoids affect behavior and physiology in rodents

Comparative Pharmacology of Cannabinoids in Rodent Models

['FUNDING_R01'] · RESEARCH TRIANGLE INSTITUTE · NIH-10314038

This study looks at how THC, a compound found in cannabis, affects the bodies and behaviors of different types of rodents, helping us understand how these effects might vary between males and females.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorRESEARCH TRIANGLE INSTITUTE (nih funded)
Locations1 site (RESEARCH TRIANGLE PARK, UNITED STATES)
Trial IDNIH-10314038 on ClinicalTrials.gov

What this research studies

This research explores the effects of cannabinoids, specifically THC, on the physiology and behavior of rodents. By using rodent models, the study aims to uncover the mechanisms behind the varying responses to THC based on sex and species. The research involves detailed assessments of physiological parameters like temperature and heart function, as well as behavioral responses to THC. The findings could provide insights into how cannabinoids interact with the endocannabinoid system and influence behavior.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals interested in the therapeutic applications of cannabinoids or those affected by conditions related to cannabinoid use.

Not a fit: Patients who do not use cannabinoids or are not interested in their effects may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of cannabinoid effects, potentially informing safer therapeutic uses for patients.

How similar studies have performed: Previous research has shown success in understanding cannabinoid effects in animal models, making this approach both relevant and promising.

Where this research is happening

RESEARCH TRIANGLE PARK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.