Investigating how cannabidiol affects stress regulation

Pathophysiological mechanisms of cannabidiol in stress regulation

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-11108369

This study is looking at how CBD might help young adults who are dealing with a lot of stress, to see if it can make it easier for them to handle stressful situations and improve their overall well-being.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11108369 on NIH RePORTER

What this research studies

This research explores the effects of cannabidiol (CBD) on stress regulation, particularly in young adults who are at high risk for stress-related disorders. It aims to understand the mechanisms by which CBD interacts with the brain's stress response systems, including pathways that are often dysregulated in anxiety and stress disorders. By examining how CBD can modulate stress reactivity, the research seeks to identify new therapeutic strategies that could improve treatment outcomes for individuals suffering from stress-related issues. Participants may receive CBD and undergo assessments to evaluate its impact on their stress responses.

Who could benefit from this research

Good fit: Ideal candidates for this research are young adults aged 21 and older who experience stress-related disorders or heightened stress responses.

Not a fit: Patients who do not experience stress-related disorders or who are not within the specified age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new, effective treatments for managing stress and anxiety without the side effects associated with current medications.

How similar studies have performed: Previous studies have shown promising results regarding the anxiolytic effects of CBD, suggesting that this approach may be effective in treating stress-related disorders.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.