Investigating how cancer cells use nitrogen for growth
Official title: Exploring the Role of Nitrogen Metabolism in Cancer
Funded at Sloan-Kettering Inst Can Research · NIH-10888397 · Data updated 2026-11-12
This study looks at how cancer cells use a substance called glutamine to help them grow and stay alive, with the hope of finding new ways to treat cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2030 |
| Funding year | 2024 |
| Award (this year) | $1,008,900 |
| NIH project number | 5R35CA283988-02 |
| Project ID | NIH-10888397 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with various types of cancer who may benefit from novel metabolic-targeted therapies.
✕Less likely to help
Patients with non-cancerous conditions or those whose cancer is not influenced by metabolic processes may not receive benefit from this research.
What this research studies
This research explores the metabolic processes of cancer cells, particularly focusing on how they utilize nitrogen from glutamine to support their growth and survival. By examining the conversion of glutamine into other compounds, the study aims to understand how cancer cells maintain their energy and produce necessary building blocks for cellular functions. The research employs advanced techniques to analyze the metabolic pathways involved, which could lead to new insights into cancer treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches that target cancer cell metabolism, potentially improving treatment outcomes for patients.
How similar studies have gone: Previous research has shown promising results in targeting cancer metabolism, indicating that this approach could lead to significant advancements in cancer treatment.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Thompson, Craig B — Sloan-Kettering Inst Can Research
- Study coordinator: Thompson, Craig B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.