Investigating how cancer cells adapt their metabolism to resist treatment
Cancer Metabolism Core
This study is looking at how pancreatic cancer cells change their metabolism to resist treatments, with the goal of finding weaknesses that could help develop better therapies for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma Hlth Sciences Ctr NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project ID | NIH-10926944 on NIH RePORTER |
What this research studies
This research focuses on understanding the metabolic changes that occur in pancreatic cancer cells, specifically pancreatic ductal adenocarcinoma (PDAC), which lead to resistance against therapies. By utilizing advanced techniques such as metabolomics and various assays, the research aims to identify specific metabolic vulnerabilities in cancer cells. Patients may benefit from insights gained through this research, which could lead to more effective treatment strategies tailored to combat therapy resistance. The research will involve analyzing both cell lines and human tumor tissues to gather comprehensive data on metabolic alterations.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with pancreatic ductal adenocarcinoma who are undergoing treatment.
Not a fit: Patients with other types of cancer or those not diagnosed with pancreatic ductal adenocarcinoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment approaches that overcome resistance in pancreatic cancer, potentially improving patient outcomes.
How similar studies have performed: Previous research has shown promise in understanding metabolic adaptations in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Oklahoma City, United States
- University of Oklahoma Hlth Sciences Ctr — Oklahoma City, United States (Active)
Researchers
- Principal investigator: Singh, Pankaj Kumar — University of Oklahoma Hlth Sciences Ctr
- Study coordinator: Singh, Pankaj Kumar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.