Investigating how cancer-associated fibroblasts affect thyroid cancer.
Official title: The Role of Cancer-Associated Fibroblasts in Thyroid Carcinoma
Funded at Vanderbilt University Medical Center · NIH-11014028 · Data updated 2026-11-12
This study is looking at how certain cells in the thyroid can affect the growth of thyroid cancer, with the hope of finding new ways to improve treatment for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $242,249 |
| NIH project number | 3R01CA272875-03S1 |
| Project ID | NIH-11014028 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with thyroid carcinoma, particularly those with specific genetic markers like the BRAF gene.
✕Less likely to help
Patients with benign thyroid conditions or those without a diagnosis of thyroid carcinoma may not receive any benefit from this research.
What this research studies
This research focuses on understanding the role of cancer-associated fibroblasts in thyroid carcinoma, which are cells that can influence tumor growth and progression. The study aims to analyze the interactions between these fibroblasts and cancer cells, potentially revealing new insights into how thyroid cancer develops and progresses. By examining tissue samples and utilizing advanced laboratory techniques, the research seeks to identify specific biological markers that could lead to improved treatment strategies for patients with thyroid cancer.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic targets and improved treatment options for patients with thyroid carcinoma.
How similar studies have gone: Other research has shown promising results in understanding the role of fibroblasts in various cancers, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Weiss, Vivian Lee — Vanderbilt University Medical Center
- Study coordinator: Weiss, Vivian Lee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.