Investigating how calcium channels affect obesity and metabolism
Store-operated Orai3 calcium channels in metabolism and obesity
['FUNDING_OTHER'] · LSU HEALTH SCIENCES CENTER · NIH-11292711
This study is looking at how a specific calcium channel in our cells affects fat storage and energy use, with the hope of finding new, gentle ways to help people manage obesity and heart-related issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LSU HEALTH SCIENCES CENTER (nih funded) |
| Locations | 1 site (NEW ORLEANS, UNITED STATES) |
| Trial ID | NIH-11292711 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of Orai3 calcium channels in fat metabolism and obesity. By studying genetically modified mice, the researchers aim to uncover how these channels influence energy balance, fat accumulation, and thermogenesis. The project seeks to develop non-invasive treatment methods for obesity and related cardiovascular diseases, which could lead to significant advancements in managing these conditions. Patients may benefit from insights into new therapeutic approaches that target calcium signaling pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or related metabolic disorders, such as type 2 diabetes.
Not a fit: Patients who are not affected by obesity or metabolic disorders may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments for obesity and its related health issues.
How similar studies have performed: Other research has shown promising results in targeting calcium signaling for metabolic disorders, indicating potential for success in this novel approach.
Where this research is happening
NEW ORLEANS, UNITED STATES
- LSU HEALTH SCIENCES CENTER — NEW ORLEANS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PATHAK, TRAYAMBAK — LSU HEALTH SCIENCES CENTER
- Study coordinator: PATHAK, TRAYAMBAK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus