Investigating how cadmium exposure affects lung fibrosis development
Cadmium-potentiated metabolic reprogramming in pathogenesis of lung fibrosis
This study is looking at how exposure to cadmium, a harmful metal, affects lung health and can lead to scarring in the lungs, especially for people who have had respiratory infections like RSV, to help find better ways to protect and treat those at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11089453 on NIH RePORTER |
What this research studies
This research explores the impact of cadmium, a toxic metal, on lung health, particularly its role in the development of lung fibrosis. The study examines how cadmium exposure alters metabolic processes in the lungs, potentially leading to inflammation and fibrotic changes. By analyzing biological responses in lung cells, the research aims to understand the mechanisms by which cadmium contributes to lung diseases, especially in individuals with a history of respiratory infections like RSV. The findings could help identify at-risk populations and inform future treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of lung disease, particularly those exposed to cadmium or with respiratory infections.
Not a fit: Patients without any history of lung disease or exposure to cadmium are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of lung fibrosis, particularly in patients exposed to environmental toxins.
How similar studies have performed: Previous research has shown that environmental toxins can significantly impact lung health, suggesting that this approach may yield valuable insights.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Go Kang, Young-Mi — Emory University
- Study coordinator: Go Kang, Young-Mi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.