Investigating how breathing problems after a stroke affect thinking skills in older adults with Alzheimer's disease.
Stroke Disordered Breathing and its Impact on Cognitive Decline in Aging, Alzheimer's Disease and Cerebral Amyloid Angiopathy
This study is looking at how breathing problems after a stroke might affect thinking and memory in older adults, especially those with Alzheimer's or certain brain conditions, to find ways to help improve both breathing and brain health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10875715 on NIH RePORTER |
What this research studies
This research explores the connection between breathing difficulties that occur after a stroke and cognitive decline in older adults, particularly those with Alzheimer's disease and cerebral amyloid angiopathy. The study aims to understand how these breathing issues impact recovery and cognitive function over time. By using animal models, researchers will investigate the mechanisms behind stroke-induced respiratory dysfunction and its effects on brain health. The ultimate goal is to develop interventions that could improve breathing and, in turn, enhance cognitive outcomes for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who have experienced a stroke and may also have Alzheimer's disease or related conditions.
Not a fit: Patients who are younger than 65 or those without a history of stroke or neurodegenerative diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve cognitive function and quality of life for older adults recovering from strokes.
How similar studies have performed: While the specific approach of this research is novel, there is emerging evidence that addressing respiratory dysfunction can positively impact recovery in stroke patients.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Li, Jun — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Li, Jun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.