Investigating how breast cancer and its treatment affect aging in older women

Long-Term Trajectories of Accelerated Biological Aging and Functional Decline Associated with Breast Cancer and its Treatment

NIH-funded research Kaiser Foundation Research Institute · NIH-10908645

This study is looking at how breast cancer and its treatments might affect aging and health over time in older women, so we can better understand the unique challenges faced by breast cancer survivors compared to those who haven't had cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project IDNIH-10908645 on NIH RePORTER

What this research studies

This research examines the long-term effects of breast cancer and its treatments on biological aging and functional decline in older women. By analyzing data from the Women's Health Initiative, the study aims to understand how cancer and its therapies may accelerate aging processes compared to women without a cancer history. The research will track changes in health and aging over time, focusing on factors like treatment type and intensity. This comprehensive approach will help identify specific health risks faced by breast cancer survivors.

Who could benefit from this research

Good fit: Ideal candidates for this research are older women, particularly those over 65, who have a history of invasive breast cancer.

Not a fit: Patients who are younger than 21 or do not have a history of breast cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved care strategies for older breast cancer survivors, enhancing their quality of life and longevity.

How similar studies have performed: Previous research has indicated that cancer treatments can lead to accelerated aging, suggesting that this study's approach is grounded in established findings.

Where this research is happening

Oakland, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.