NIH-funded research Fellowship grant

Investigating how brain stimulation affects cognitive issues from adolescent binge drinking

Official title: Effects of tACS on alcohol-induced cognitive and neurochemical deficits

Funded at Univ of North Carolina Chapel Hill · NIH-11035083 · Data updated 2026-11-12

This study is looking at how binge drinking during the teenage years can affect the brain's ability to adapt to new situations, using rats to understand the problem better, with the hope of finding new ways to help young people who might be struggling with these issues.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill
NIH-funded
Lab location1 site (Chapel Hill, United States)
Project startJanuary 1, 2024
Project endJuly 17, 2025
Funding year2025
Award (this year)$50,528
NIH project number5F32AA031422-02
Project IDNIH-11035083 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents under 21 who have engaged in binge drinking behaviors.

Less likely to help

Patients who have not experienced binge drinking or are over the age of 21 may not benefit from this research.

What this research studies

This research explores the cognitive impairments caused by binge drinking in adolescents, particularly focusing on behavioral flexibility, which is the ability to adapt to changing situations. Using a rat model, the study examines how adolescent intermittent exposure to alcohol affects brain structures and functions. The researchers aim to identify the underlying neural mechanisms and test new treatment approaches that could help mitigate these cognitive deficits. By understanding these effects, the research seeks to provide insights into potential interventions for affected individuals.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that improve cognitive function in adolescents who have experienced binge drinking.

How similar studies have gone: Previous research has shown promising results in understanding cognitive impairments related to alcohol use, but this specific approach using brain stimulation is relatively novel.

Where this research is happening

  • Univ of North Carolina Chapel Hill
    Chapel Hill, United States
    Active

Researchers

  • Principal investigator: Sullivan, Emily — Univ of North Carolina Chapel Hill
  • Study coordinator: Sullivan, Emily

Related research

Other NIH-funded projects on the same topics.

  • A center for coordinating data related to heart and blood health.

    This study is working on a new system to gather and analyze health information about heart and blood disorders, which could lead to better ways to diagnose and treat these conditions, ultimately helping patients like you.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-9732880

  • Healthy work design and worker well-being

    A multi-site program aims to improve the health and well-being of workers by studying how work design affects safety, stress, and quality of life.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11631666

  • Unified and fair multimodal learning for autoimmune diseases

    A patient-friendly AI approach will combine many kinds of health data to improve diagnosis and personalized care for autoimmune diseases, including lupus.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11625649

  • Structural factors linking minimum wage, COVID-19, and community violence

    A long-term study will explore whether higher minimum wages and pandemic-related economic factors are connected to changes in violence in US communities.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11624218

  • Non-invasive tears biomarker for early Alzheimer's in LMICs

    A low-cost, tear-based biomarker approach aims to detect early Alzheimer’s disease in older adults in Peru and similar settings.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11623923

  • How HPV interacts with our cells' DNA damage system and its effect on cancer

    This project looks at how high-risk HPV uses the body’s DNA repair machinery to replicate and potentially drive cancer, with the goal of finding new antiviral and cancer-fighting approaches for people affected by HPV-related diseases.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11622604

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.