Investigating how brain signaling changes after repeated mild injuries
Role of Neuronal p38 MAPK After Repetitive Mild TBI
This study is looking at how repeated mild brain injuries can affect your brain's health and function, especially focusing on a specific pathway in brain cells that might cause ongoing thinking and emotional problems, with the goal of finding new ways to help people who have experienced these injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10925220 on NIH RePORTER |
What this research studies
This research focuses on understanding the effects of repetitive mild traumatic brain injuries (mTBIs) on brain function and health. It aims to explore how a specific signaling pathway in neurons, known as p38 MAPK, is activated after these injuries and how this activation may lead to long-term cognitive and emotional issues. By studying both animal models and clinical data, the researchers hope to uncover the mechanisms behind the neurological symptoms that persist after mTBIs, which are not solely explained by the physical impact of the injuries. This could lead to new therapeutic strategies for those affected by these injuries.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced repetitive mild traumatic brain injuries and are facing cognitive or emotional challenges.
Not a fit: Patients who have not experienced any form of traumatic brain injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from long-lasting effects of mild traumatic brain injuries.
How similar studies have performed: Previous research has shown promising results in understanding brain signaling pathways after traumatic injuries, indicating that this approach may yield valuable insights.
Where this research is happening
Atlanta, United States
- Georgia Institute of Technology — Atlanta, United States (Active)
Researchers
- Principal investigator: Wood, Levi Benjamin — Georgia Institute of Technology
- Study coordinator: Wood, Levi Benjamin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.