Investigating how brain network connectivity affects seizure recurrence after surgery in temporal lobe epilepsy.
The Role of Network Connectivity in Post-Surgical Seizure Recurrence in Temporal Lobe Epilepsy
This study looks at how the connections in the brain might affect whether seizures come back after surgery for people with temporal lobe epilepsy, and it aims to help improve treatment options for those considering surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10634545 on NIH RePORTER |
What this research studies
This research explores the relationship between brain network connectivity and the recurrence of seizures in patients with temporal lobe epilepsy (TLE) who have undergone surgery. By using advanced Magnetic Resonance Imaging (MRI), the study aims to create a detailed model of brain networks in patients who remain seizure-free after surgery. The goal is to identify specific network characteristics that may predict seizure outcomes, helping to improve surgical strategies and patient care. Patients with TLE who are considering surgery may find this research particularly relevant as it seeks to enhance understanding of their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with temporal lobe epilepsy who are considering surgical intervention due to drug-resistant seizures.
Not a fit: Patients with epilepsy types other than temporal lobe epilepsy or those who are not candidates for surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical outcomes and personalized treatment plans for patients with temporal lobe epilepsy.
How similar studies have performed: Previous research has shown promising results in understanding seizure networks, suggesting that this approach may lead to significant advancements in epilepsy treatment.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Morgan, Victoria L — Vanderbilt University Medical Center
- Study coordinator: Morgan, Victoria L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.