Investigating how brain function stability is affected in Jordan's Syndrome
Homeostatic plasticity in mouse models of Jordan's Syndrome
This study is looking at how the brain keeps itself balanced and how this relates to Jordan's Syndrome, a serious condition that affects development, using mice to find ways to help improve treatments for people with this syndrome and similar issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11134580 on NIH RePORTER |
What this research studies
This research explores the concept of homeostatic plasticity, which refers to the brain's ability to stabilize its functions despite changes. It focuses on understanding how this process is linked to Jordan's Syndrome, a severe neurodevelopmental disorder. Using mouse models, the researchers will examine the molecular mechanisms that may contribute to the disorder and how they can be manipulated for potential therapies. The goal is to uncover new insights that could lead to improved treatments for individuals affected by Jordan's Syndrome and similar conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Jordan's Syndrome or related neurodevelopmental disorders.
Not a fit: Patients with neurodevelopmental disorders not related to Jordan's Syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for managing Jordan's Syndrome and potentially other neurodevelopmental disorders.
How similar studies have performed: While the specific approach to studying homeostatic plasticity in Jordan's Syndrome is novel, related research has shown promise in understanding neurodevelopmental disorders.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Davis, Graeme W — University of California, San Francisco
- Study coordinator: Davis, Graeme W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.