Investigating how brain chemicals affect sensory processing in mice
The Spatial and Temporal Scale of Neuromodulation in Mouse Sensory Cortex
This study is looking at how certain brain chemicals, called acetylcholine and norepinephrine, help mice pay attention to different senses, which could help us understand problems related to attention in conditions like Alzheimer's disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10524638 on NIH RePORTER |
What this research studies
This research explores the roles of neuromodulators, specifically acetylcholine and norepinephrine, in enhancing sensory processing in the mouse brain. By using advanced techniques to measure these chemicals alongside neural activity, the study aims to understand how their availability varies across different regions of the cortex and how this impacts performance on tasks that require attention to multiple senses. The findings could provide insights into how disruptions in these systems relate to conditions like Alzheimer's disease and other neurodevelopmental disorders.
Who could benefit from this research
Good fit: Ideal candidates for potential benefit from this research include individuals diagnosed with Alzheimer's disease or related cognitive disorders.
Not a fit: Patients with conditions unrelated to neuromodulation or sensory processing may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for neurodegenerative diseases and disorders affecting attention and sensory processing.
How similar studies have performed: Previous research has shown promising results in understanding the role of neuromodulators in sensory processing, suggesting that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Reimer, Jacob — Baylor College of Medicine
- Study coordinator: Reimer, Jacob
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.