Investigating how brain chemicals affect brain activity and blood flow.
Project 2
This study is looking at how certain brain chemicals affect brain activity and blood flow in awake mice, which could help us understand how our brains work together during different tasks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11095750 on NIH RePORTER |
What this research studies
This research explores the role of neuromodulation in brain activity by examining how neurotransmitters like acetylcholine, norepinephrine, dopamine, and serotonin influence the pial neurovascular circuit. Using advanced techniques such as optical probes and imaging, the study aims to directly measure these neurotransmitters in awake mice to understand their impact on large-scale cortical networks. By integrating neuronal activity with blood flow dynamics, the research seeks to uncover the mechanisms behind coherent oscillations in brain function.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with neurological conditions that affect brain activity and blood flow.
Not a fit: Patients with stable neurological conditions that do not involve significant alterations in brain activity or blood flow may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights into brain function and potential treatments for neurological disorders.
How similar studies have performed: Previous research has shown promising results in understanding neuromodulation and its effects on brain function, indicating that this approach has potential for significant findings.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Devor, Anna — Boston University (Charles River Campus)
- Study coordinator: Devor, Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.