Investigating how brain cells regulate sleep using zebrafish
Genetic and Neuronal Mechanisms that Regulate Zebrafish Sleep - DIVERSITY SUPPLEMENT
['FUNDING_OTHER'] · CALIFORNIA INSTITUTE OF TECHNOLOGY · NIH-11087989
This study is looking at how special brain cells called astrocytes help control sleep using baby zebrafish, and it hopes to find new ways to understand and treat sleep problems.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CALIFORNIA INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (PASADENA, UNITED STATES) |
| Trial ID | NIH-11087989 on ClinicalTrials.gov |
What this research studies
This research explores the role of astrocytes, a type of brain cell, in regulating sleep by using larval zebrafish as a model. The study employs advanced imaging techniques to observe brain activity during sleep and wakefulness, allowing researchers to understand how these cells contribute to sleep regulation. By manipulating astrocyte activity through various experimental methods, the research aims to uncover the mechanisms behind sleep homeostasis. This could lead to new insights into sleep disorders and their treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from sleep disorders or those interested in the biological mechanisms of sleep.
Not a fit: Patients who do not have sleep disorders or are not interested in the biological aspects of sleep may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for sleep disorders, improving the quality of life for affected patients.
How similar studies have performed: Previous research has shown promising results in understanding sleep mechanisms using animal models, indicating that this approach could yield valuable insights.
Where this research is happening
PASADENA, UNITED STATES
- CALIFORNIA INSTITUTE OF TECHNOLOGY — PASADENA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PROBER, DAVID AARON — CALIFORNIA INSTITUTE OF TECHNOLOGY
- Study coordinator: PROBER, DAVID AARON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.