Investigating how brain cells influence social behavior as people age

Cellular and circuit investigation of age-dependent social behaviors

NIH-funded research Yale University · NIH-11147004

This study is looking at how certain brain cells help shape social behaviors in babies and young kids, so we can better understand how these connections develop and how they might relate to mental health issues later on.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11147004 on NIH RePORTER

What this research studies

This research explores the neural mechanisms behind social behavior development, focusing on specific brain cells known as POMC neurons. By using advanced imaging techniques, the study aims to understand how these neurons respond to social interactions at different ages, particularly in infants and juveniles. The researchers will observe these neurons in real-time to see how they influence social behaviors and emotional responses. This could provide insights into the development of mental health conditions linked to social relationship disruptions.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals aged 0-20 years who may experience social behavior challenges or mental health conditions.

Not a fit: Patients who are not within the age range of 0-20 years or do not have social behavior challenges may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment of mental health issues related to social behavior across different age groups.

How similar studies have performed: Previous research has shown promising results in understanding the role of specific brain cells in social behavior, suggesting that this approach could yield valuable insights.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.