NIH-funded research R21 grant

Investigating how brain cells influence social behavior as people age

Official title: Cellular and circuit investigation of age-dependent social behaviors

Funded at Yale University · NIH-11147004 · Data updated 2026-11-12

This study is looking at how certain brain cells help shape social behaviors in babies and young kids, so we can better understand how these connections develop and how they might relate to mental health issues later on.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startJune 16, 2025
Project endJune 15, 2027
Funding year2025
Award (this year)$461,084
NIH project number1R21MH138997-01A1
Project IDNIH-11147004 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals aged 0-20 years who may experience social behavior challenges or mental health conditions.

Less likely to help

Patients who are not within the age range of 0-20 years or do not have social behavior challenges may not benefit from this research.

What this research studies

This research explores the neural mechanisms behind social behavior development, focusing on specific brain cells known as POMC neurons. By using advanced imaging techniques, the study aims to understand how these neurons respond to social interactions at different ages, particularly in infants and juveniles. The researchers will observe these neurons in real-time to see how they influence social behaviors and emotional responses. This could provide insights into the development of mental health conditions linked to social relationship disruptions.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment of mental health issues related to social behavior across different age groups.

How similar studies have gone: Previous research has shown promising results in understanding the role of specific brain cells in social behavior, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Dietrich, Marcelo — Yale University
  • Study coordinator: Dietrich, Marcelo

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.