Investigating how brain blood vessels respond to neuronal activity
Project 1
This study is looking at how blood vessels in the brain work together with nerve activity in mice, which could help us learn more about brain health and diseases that affect people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University (Charles River Campus) NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11095747 on NIH RePORTER |
What this research studies
This research focuses on understanding the pial neurovascular circuit in mice, which involves the interaction between blood vessels and neuronal activity. Using advanced imaging techniques and data analysis, the team will study how these blood vessels oscillate and respond to different sensory stimuli. By examining the dynamics of blood flow and vessel behavior, the research aims to uncover fundamental physiological principles that could inform our understanding of brain function. Patients may benefit from insights gained about brain health and disease mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with neurological disorders or those interested in brain health.
Not a fit: Patients with conditions unrelated to brain function or vascular health may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of brain function and potential new treatments for neurological conditions.
How similar studies have performed: Other research has shown success in using similar imaging techniques to study brain function, indicating that this approach is promising.
Where this research is happening
Boston, United States
- Boston University (Charles River Campus) — Boston, United States (Active)
Researchers
- Principal investigator: Kleinfeld, David — Boston University (Charles River Campus)
- Study coordinator: Kleinfeld, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.