Investigating how bone marrow affects kidney disease
Official title: Targeting bone marrow to treat renal disease
Funded at University of Texas Med Br Galveston · NIH-10991721 · Data updated 2026-11-12
This study is looking at how the immune system in your bone marrow affects kidney problems like idiopathic nephrotic syndrome and FSGS, with the goal of finding new ways to help improve treatments for people dealing with these conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Med Br Galveston NIH-funded |
| Lab location | 1 site (Galveston, United States) |
| Project start | January 1, 2023 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $424,750 |
| NIH project number | 5R01DK132072-03 |
| Project ID | NIH-10991721 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults diagnosed with idiopathic nephrotic syndrome or focal segmental glomerular sclerosis.
✕Less likely to help
Patients with kidney diseases unrelated to immune system dysfunction may not benefit from this research.
What this research studies
This research focuses on understanding the role of the bone marrow immune system in idiopathic nephrotic syndrome, particularly in cases like focal segmental glomerular sclerosis (FSGS). The study aims to identify immune signatures and mechanisms that contribute to kidney disease progression and recurrence after transplantation. By examining the relationship between bone marrow-derived cells and kidney function, the research seeks to uncover potential therapeutic targets that could lead to more effective treatments for patients suffering from these conditions.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that specifically target the immune factors involved in kidney diseases, improving patient outcomes.
How similar studies have gone: Previous research has shown promising results in targeting immune mechanisms in kidney diseases, suggesting that this approach may yield significant advancements.
Where this research is happening
-
University of Texas Med Br Galveston
Galveston, United States Active
Researchers
- Principal investigator: Reiser, Jochen — University of Texas Med Br Galveston
- Study coordinator: Reiser, Jochen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.