Investigating how bone-implant loading affects prosthetic function
Official title: Dynamic Bone-Implant Loading in Osseointegrated Prostheses
Funded at University of Colorado Denver · NIH-10838600 · Data updated 2026-11-12
This study is looking at how well prosthetic limbs that are attached directly to the bone work during everyday activities, so we can make them better and help people avoid problems like loosening or fractures.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | May 15, 2023 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $144,400 |
| NIH project number | 5R03HD111012-02 |
| Project ID | NIH-10838600 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with transfemoral or transtibial amputations who are using or considering osseointegrated prostheses.
✕Less likely to help
Patients with traditional socket-based prostheses or those who do not have amputations may not benefit from this research.
What this research studies
This research focuses on osseointegrated prostheses, which are directly attached to the bone, improving the connection between the prosthetic limb and the body. The study aims to develop advanced models to measure the loading at the bone-implant interface during daily activities, which is crucial for preventing complications like implant loosening or fractures. By analyzing existing data, the researchers will create a platform that incorporates muscle forces and daily living activities to better understand how these factors influence the performance of the prosthesis. This could lead to improved designs and better outcomes for patients using these types of prosthetics.
Why it matters
Potential benefit: If successful, this research could enhance the functionality and longevity of osseointegrated prostheses, significantly improving patients' quality of life.
How similar studies have gone: Previous research has shown promising results in improving function and quality of life with osseointegrated prostheses, indicating that this approach has potential for further advancements.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Gaffney, Brecca — University of Colorado Denver
- Study coordinator: Gaffney, Brecca
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.