Investigating how body fat affects frailty in older patients with lung disease

Role of visceral adipose tissue in frailty among patients with Idiopathic Pulmonary Fibrosis

['FUNDING_OTHER'] · UNIVERSITY OF PENNSYLVANIA · NIH-10912580

This study is looking at how extra body fat might affect weakness in older adults with idiopathic pulmonary fibrosis (IPF), and it hopes to find ways to help improve their health and well-being.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-10912580 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the impact of body composition, particularly visceral adipose tissue, on frailty in patients with idiopathic pulmonary fibrosis (IPF). The study aims to identify how increased body fat may contribute to frailty, which is a significant concern for older adults with IPF. By using bioelectrical impedance analysis, researchers will assess body composition and its relationship to frailty, potentially leading to new insights into managing this condition. The findings could help in developing targeted interventions to improve patient outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 65 and above who have been diagnosed with idiopathic pulmonary fibrosis.

Not a fit: Patients who are younger than 65 or do not have idiopathic pulmonary fibrosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management strategies for frailty in patients with idiopathic pulmonary fibrosis, enhancing their quality of life.

How similar studies have performed: Previous research has indicated a link between body composition and frailty, suggesting that this approach may yield valuable insights, although the specific focus on visceral adipose tissue in IPF is relatively novel.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.