Investigating how body fat affects colorectal cancer outcomes
Body composition and adiposity-associated thromboinflammation in colorectal cancer prognosis
This study is looking at how being overweight might affect the outcomes of colorectal cancer by using special technology to get a better picture of body fat and muscle, and it hopes to find new ways to help treat patients based on their unique needs.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11082462 on NIH RePORTER |
What this research studies
This research explores the connection between obesity and colorectal cancer prognosis by examining body composition beyond traditional measures like BMI. It utilizes advanced artificial intelligence to analyze CT scans for precise measurements of fat distribution and muscle mass. The study also investigates a new biological pathway called thromboinflammation, which may influence cancer progression in obese patients. By understanding these factors, the research aims to improve treatment strategies tailored to individual patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with colorectal cancer who also have obesity or are overweight.
Not a fit: Patients without colorectal cancer or those who are not classified as obese may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for colorectal cancer patients with obesity.
How similar studies have performed: Previous research has shown promising results in using advanced imaging and biological pathways to improve cancer treatment outcomes, suggesting this approach could be impactful.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Byrd, Doratha Armenthus — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Byrd, Doratha Armenthus
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.