Investigating how blood vessel issues affect movement problems in Alzheimer's disease
Vascular contribution to white matter lesions and motor dysfunction in AD and ADRD
This study is looking at how problems with blood vessels might affect movement difficulties in people with Alzheimer's Disease, hoping to find new ways to help manage these issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project ID | NIH-10501969 on NIH RePORTER |
What this research studies
This research explores the relationship between vascular health and motor dysfunction in patients with Alzheimer's Disease (AD). It aims to understand how changes in blood vessels and white matter lesions contribute to movement difficulties, which can occur even in the early stages of AD. By studying these mechanisms in an AD mouse model, the research seeks to uncover the underlying causes of motor impairment associated with the disease. This could lead to new insights into how to better manage or treat these symptoms in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's Disease, particularly those experiencing motor dysfunction.
Not a fit: Patients with Alzheimer's Disease who do not exhibit any motor dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing motor dysfunction in Alzheimer's patients, enhancing their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the connection between vascular health and motor dysfunction in other neurological diseases, suggesting potential for success in this area as well.
Where this research is happening
Newark, UNITED STATES
- Rutgers Biomedical and Health Sciences — Newark, United States (Active)
Researchers
- Principal investigator: Ahn, Hyung Jin — Rutgers Biomedical and Health Sciences
- Study coordinator: Ahn, Hyung Jin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.