Investigating how blood vessel health affects thinking skills in Lewy body dementias
Cerebrovascular contributions to cognitive impairment in Lewy body dementias
This study is looking at how the health of blood vessels in the brain affects thinking and memory problems in people with Lewy body dementias, like Parkinson’s Disease Dementia, to find early signs that could help with diagnosis and treatment.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lovelace Biomedical Research Institute NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project ID | NIH-10560481 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of cerebrovascular health in cognitive decline associated with Lewy body dementias, such as Parkinson’s Disease Dementia and Dementia with Lewy Bodies. By using advanced imaging techniques, the study aims to identify early biomarkers that can help in the diagnosis and treatment of these conditions. The researchers will measure how well blood vessels respond to challenges and how quickly blood reaches brain tissues, which may reveal important insights into cognitive impairment. The goal is to improve patient outcomes by identifying specific cerebrovascular issues that could be targeted for intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson’s Disease Dementia or Dementia with Lewy Bodies who are experiencing cognitive decline.
Not a fit: Patients without a diagnosis of Lewy body dementias or those with other types of dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and more effective treatments for patients with Lewy body dementias.
How similar studies have performed: Previous research has shown promise in using cerebrovascular measures to understand cognitive decline, suggesting that this approach may yield valuable insights.
Where this research is happening
Albuquerque, United States
- Lovelace Biomedical Research Institute — Albuquerque, United States (Active)
Researchers
- Principal investigator: Ryman, Sephira — Lovelace Biomedical Research Institute
- Study coordinator: Ryman, Sephira
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.