Investigating how blood vessel dysfunction affects recovery after a stroke

Neurophotonic Advances for Mechanistic Investigation of the Role of Capillary Dysfunction in Stroke Recovery

['FUNDING_R01'] · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · NIH-10913639

This study is looking at how problems with tiny blood vessels in the brain affect recovery after a stroke, and it aims to help improve treatments for stroke patients by learning more about how these blood vessels work during healing.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBOSTON UNIVERSITY (CHARLES RIVER CAMPUS) (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10913639 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the role of capillary dysfunction in the recovery process following a stroke. Using advanced neuroimaging techniques like 2-photon microscopy, the study aims to explore how changes in blood vessels and their response to brain activity impact functional recovery. By monitoring stroke patients over time, researchers hope to uncover the biological mechanisms that facilitate recovery, which could lead to improved treatment strategies. The study emphasizes the importance of understanding neurovascular coupling in damaged brain regions to enhance patient outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have recently experienced a stroke and are in the recovery phase.

Not a fit: Patients who have not had a stroke or are in the very acute phase of stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better treatment approaches that enhance recovery for stroke patients.

How similar studies have performed: Previous research has shown promise in using neuroimaging techniques to understand stroke recovery, indicating that this approach could yield valuable insights.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.