Investigating how blood pressure control affects heart failure risk in adults with type 2 diabetes.
Official title: Cardiac biomarkers, intensive blood pressure treatment and risk of adverse cardiovascular outcomes in type 2 diabetes, a secondary analysis of the ACCORD BP
Funded at Ut Southwestern Medical Center · NIH-10901969 · Data updated 2026-11-12
This study is looking at how keeping blood pressure in check can help prevent heart failure in adults with type 2 diabetes, and it will check blood samples to find out if certain markers can help identify those who might need extra help with their blood pressure management.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $124,885 |
| NIH project number | 5R21HL169708-02 |
| Project ID | NIH-10901969 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with type 2 diabetes and are at risk for heart failure.
✕Less likely to help
Patients who do not have type 2 diabetes or those who are not at risk for heart failure may not benefit from this research.
What this research studies
This research focuses on understanding the relationship between blood pressure control and the risk of heart failure in adults with type 2 diabetes. It aims to identify high-risk individuals who may benefit more from intensive blood pressure management by measuring specific cardiac biomarkers. Participants from the ACCORD-BP trial will have their blood samples analyzed for these biomarkers at various points in time. The goal is to determine if these biomarkers can guide treatment decisions to better prevent heart failure.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing heart failure in adults with type 2 diabetes.
How similar studies have gone: Previous research has shown that cardiac biomarkers can be useful in predicting heart failure risk, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Pandey, Ambarish — Ut Southwestern Medical Center
- Study coordinator: Pandey, Ambarish
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.