Investigating how biological age affects uterine function during pregnancy
The Clock is Ticking: Epigenetic Age Acceleration as a Biomarker of Uterine Function in Pregnancy
['FUNDING_OTHER'] · UNIVERSITY OF ARIZONA · NIH-10887655
This study is looking at how your biological age, which is based on changes in your DNA, affects how your uterus works during childbirth, especially for women over 35, to see if it can better predict any complications than just your actual age.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ARIZONA (nih funded) |
| Locations | 1 site (TUCSON, UNITED STATES) |
| Trial ID | NIH-10887655 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how biological age, as measured by DNA methylation patterns, impacts uterine function in women over 35 years old during childbirth. It aims to determine if biological age can serve as a more accurate predictor of complications related to labor and delivery compared to chronological age. By analyzing blood samples and other biological markers, the study seeks to uncover the relationship between epigenetic age and maternal health outcomes, particularly in the context of increased risks associated with advanced maternal age.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women aged 35 years and older.
Not a fit: Patients who are younger than 35 years old or not currently pregnant may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved predictions of childbirth complications for older mothers, allowing for better management and care during pregnancy.
How similar studies have performed: Previous research has indicated that biological markers like epigenetic age can provide valuable insights into health outcomes, suggesting that this approach may yield significant findings.
Where this research is happening
TUCSON, UNITED STATES
- UNIVERSITY OF ARIZONA — TUCSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ERICKSON, ELISE N — UNIVERSITY OF ARIZONA
- Study coordinator: ERICKSON, ELISE N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.