Investigating how beta agonists can help treat chronic kidney disease
Official title: The role of beta agonists in the treatment of chronic kidney disease
Funded at Ralph H Johnson VA Medical Center · NIH-10975953 · Data updated 2026-11-12
This study is looking at how a certain type of receptor in the body might help improve kidney function for people with chronic kidney disease, especially after kidney damage from conditions like diabetes, and it may involve patients trying out new treatments to see if they can help their kidneys heal better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ralph H Johnson VA Medical Center NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project start | October 1, 2022 |
| Project end | September 30, 2026 |
| Funding year | 2025 |
| NIH project number | 5I01CX002391-03 |
| Project ID | NIH-10975953 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic kidney disease, particularly those with underlying conditions like diabetes.
✕Less likely to help
Patients with acute kidney injury or those without chronic kidney disease may not benefit from this research.
What this research studies
This research focuses on the potential of beta 2 adrenergic receptors to improve kidney function in patients with chronic kidney disease (CKD). It aims to explore how these receptors can accelerate recovery of glomerular function after injury, particularly in the context of diseases like diabetes that damage kidney cells. By analyzing gene expression related to mitochondrial function, the study seeks to identify new therapeutic targets that could restore podocyte health and improve patient outcomes. Patients may be involved in trials assessing the effectiveness of beta agonists in enhancing kidney recovery.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve kidney function and quality of life for patients with chronic kidney disease.
How similar studies have gone: Previous research has shown promise in targeting beta adrenergic receptors for kidney recovery, suggesting that this approach could be effective.
Where this research is happening
-
Ralph H Johnson VA Medical Center
Charleston, United States Active
Researchers
- Principal investigator: Lipschutz, Joshua H — Ralph H Johnson VA Medical Center
- Study coordinator: Lipschutz, Joshua H
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.