Investigating how bat-derived viruses affect human health
Understanding the Tropism and Pathogenesis of Pararubulaviruses
This study is looking at how certain viruses from bats can affect human cells, and it's for anyone interested in understanding how these viruses work and how we might protect ourselves from them in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11040635 on NIH RePORTER |
What this research studies
This research focuses on understanding the interaction between emerging bat-derived viruses, known as pararubulaviruses, and human cells. The team will use advanced techniques, including organ explant models and molecular biology tools, to explore how these viruses enter human cells and the pathways they use to cause disease. By developing a pathogenic animal model that mimics human disease, the researchers aim to uncover critical information that could lead to effective medical countermeasures against these viruses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who may be at risk of exposure to pararubulaviruses, particularly those with compromised immune systems or underlying health conditions.
Not a fit: Patients who are not at risk of exposure to these specific bat-derived viruses or who do not have any related health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of effective treatments or vaccines for diseases caused by pararubulaviruses.
How similar studies have performed: Other research has shown success in understanding viral pathogenesis through similar innovative approaches, indicating potential for impactful findings in this area.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Lee, Benhur — Icahn School of Medicine at Mount Sinai
- Study coordinator: Lee, Benhur
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.